Clarifying the Ghrelin System’s Ability to Regulate Feeding Behaviours Despite Enigmatic Spatial Separation of the GHSR and Its Endogenous Ligand

Clarifying the Ghrelin System’s Ability to Regulate Feeding Behaviours Despite Enigmatic Spatial Separation of the GHSR and Its Endogenous Ligand

Ghrelin is a hormone predominantly produced in and secreted from the stomach. Ghrelin is involved in many physiological processes including feeding, the stress response, and in modulating learning, memory and motivational processes. Ghrelin does this by binding to its receptor, the growth hormone se...

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Bibliographic Details
Main Authors: Alexander Edwards, Alfonso Abizaid
Format: Article
Language:English
Published: MDPI AG 2017-04-01
Series:International Journal of Molecular Sciences
Subjects:
feeding
ghrelin
GHSR
blood brain barrier
vagal afferents
circumventricular organs
central ghrelin synthesis
GHSR heterodimerization
GHSR constitutive activity
Online Access:http://www.mdpi.com/1422-0067/18/4/859

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http://www.mdpi.com/1422-0067/18/4/859

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