Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases

Neurodegenerative diseases are linked to the accumulation of specific protein aggregates, suggesting an intimate connection between injured brain and loss of proteostasis. Proteostasis refers to all the processes by which cells control the abundance and folding of the proteome thanks to a wide netwo...

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Bibliographic Details
Main Authors: Marta Pajares, Antonio Cuadrado, Ana I. Rojo
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231716304050