Route of Vaccine Administration Alters Antigen Trafficking but Not Innate or Adaptive Immunity

Route of Vaccine Administration Alters Antigen Trafficking but Not Innate or Adaptive Immunity

Summary: Although intramuscular (i.m.) administration is the most commonly used route for licensed vaccines, subcutaneous (s.c.) delivery is being explored for several new vaccines under development. Here, we use rhesus macaques, physiologically relevant to humans, to identify the anatomical compart...

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Bibliographic Details
Main Authors: Sebastian Ols, Lifei Yang, Elizabeth A. Thompson, Pradeepa Pushparaj, Karen Tran, Frank Liang, Ang Lin, Bengt Eriksson, Gunilla B. Karlsson Hedestam, Richard T. Wyatt, Karin Loré
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720302928

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http://www.sciencedirect.com/science/article/pii/S2211124720302928

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