Genetic context determines susceptibility to intraocular pressure elevation in a mouse pigmentary glaucoma

<p>Abstract</p> <p>Background</p> <p>DBA/2J (D2) mice develop an age-related form of glaucoma. Their eyes progressively develop iris pigment dispersion and iris atrophy followed by increased intraocular pressure (IOP) and glaucomatous optic nerve damage. Mutant alleles...

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Bibliographic Details
Main Authors: Cosma Ioan M, Mao Mao, Libby Richard T, Anderson Michael G, Wilson Larry A, Smith Richard S, John Simon WM
Format: Article
Language:English
Published: BMC 2006-07-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/4/20