Characterization and engineering of Streptomyces griseofuscus DSM 40191 as a potential host for heterologous expression of biosynthetic gene clusters

Abstract Streptomyces griseofuscus DSM 40191 is a fast growing Streptomyces strain that remains largely underexplored as a heterologous host. Here, we report the genome mining of S. griseofuscus, followed by the detailed exploration of its phenotype, including the production of native secondary meta...

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Bibliographic Details
Main Authors: Tetiana Gren, Christopher M. Whitford, Omkar S. Mohite, Tue S. Jørgensen, Eftychia E. Kontou, Julie B. Nielsen, Sang Yup Lee, Tilmann Weber
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-97571-2