The effect of paclitaxel alone and in combination with cycloheximide on the frequency of premature centromere division in vitro

Premature centromere division (PCD) can be viewed as a manifestation of chromosome instability. In order to evaluate the ability of Paclitaxel (Ptx) and Cycloheximide (Cy) to induce PCD we used a cytokinesis block micronucleus assay (CBMN), fluorescent in situ hybridization (FISH), and the chromosom...

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Bibliographic Details
Main Authors: Bajić V., Stanimirović Z., Stevanović Jevrosima, Milićević Zorka, Živković Lada, Spremo-Potparević Biljana
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2010-01-01
Series:Archives of Biological Sciences
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2010/0354-46641001063B.pdf