Circulatory mitochondrial DNA is a pro-inflammatory agent in maintenance hemodialysis patients.

Chronic inflammation is highly prevalent in maintenance hemodialysis (MHD) patients, and it has been shown to be a strong predictor of morbidity and mortality. Mitochondrial DNA (mtDNA) released into circulation after cell damage can promote inflammation in patients and animal models. However, the r...

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Bibliographic Details
Main Authors: Hongdi Cao, Hong Ye, Zhiping Sun, Xia Shen, Zongwei Song, Xiaochun Wu, Weichun He, Chunsun Dai, Junwei Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4259325?pdf=render