FKBP5 and early life stress affect the hippocampus by an age-dependent mechanism

FKBP5 and early life stress affect the hippocampus by an age-dependent mechanism

Early life stress (ELS) adversely affects the brain and is commonly associated with the etiology of mental health disorders, like depression. In addition to the mood-related symptoms, patients with depression show dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, increased peripheral i...

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Bibliographic Details
Main Authors: Marangelie Criado-Marrero, Taylor M. Smith, Lauren A. Gould, Sojeong Kim, Hannah J. Penny, Zheying Sun, Danielle Gulick, Chad A. Dickey, Laura J. Blair
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Hippocampus
FKBP5
Early life stress
Maternal separation
Glucocorticoids
Stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354620301083

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http://www.sciencedirect.com/science/article/pii/S2666354620301083

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