NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation
NMDARs and MAGUK proteins are capable of forming higher-order protein assemblies, however their organisation in the intact brain is unclear. Here, Frank et al. identify mouse and human supercomplexes and discover their mechanism of assembly using genetic tagging and affinity purification.
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2016-04-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms11264 |