Hypoxia-induced mitochondrial abnormalities in cells of the placenta.

<h4>Introduction</h4>Impaired utero-placental perfusion is a well-known feature of early preeclampsia and is associated with placental hypoxia and oxidative stress. Although aberrations at the level of the mitochondrion have been implicated in PE pathophysiology, whether or not hypoxia-i...

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Main Authors: Philippe Vangrieken, Salwan Al-Nasiry, Aalt Bast, Pieter A Leermakers, Christy B M Tulen, Ger M J Janssen, Iris Kaminski, Iris Geomini, Titus Lemmens, Paul M H Schiffers, Frederik J van Schooten, Alex H V Remels
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0245155