Staphylococcus aureus proteins Sbi and Efb recruit human plasmin to degrade complement C3 and C3b.

Staphylococcus aureus proteins Sbi and Efb recruit human plasmin to degrade complement C3 and C3b.

Upon host infection, the human pathogenic microbe Staphylococcus aureus (S. aureus) immediately faces innate immune reactions such as the activated complement system. Here, a novel innate immune evasion strategy of S. aureus is described. The staphylococcal proteins surface immunoglobulin-binding pr...

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Bibliographic Details
Main Authors: Tina K Koch, Michael Reuter, Diana Barthel, Sascha Böhm, Jean van den Elsen, Peter Kraiczy, Peter F Zipfel, Christine Skerka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23071827/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23071827/?tool=EBI

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