T-helper cell-mediated proliferation and cytokine responses against recombinant Merkel cell polyomavirus-like particles.

T-helper cell-mediated proliferation and cytokine responses against recombinant Merkel cell polyomavirus-like particles.

The newly discovered Merkel Cell Polyomavirus (MCPyV) resides in approximately 80% of Merkel cell carcinomas (MCC). Causal role of MCPyV for this rare and aggressive skin cancer is suggested by monoclonal integration and truncation of large T (LT) viral antigen in MCC cells. The mutated MCPyV has re...

Full description

Bibliographic Details
Main Authors: Arun Kumar, Tingting Chen, Sari Pakkanen, Anu Kantele, Maria Söderlund-Venermo, Klaus Hedman, Rauli Franssila
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3185038?pdf=render

Internet

http://europepmc.org/articles/PMC3185038?pdf=render

Similar Items