High-frequency stimulation of nucleus accumbens changes in dopaminergic reward circuit.

Deep brain stimulation (DBS) of the nucleus accumbens (NAc) is a potential remedial therapy for drug craving and relapse, but the mechanism is poorly understood. We investigated changes in neurotransmitter levels during high frequency stimulation (HFS) of the unilateral NAc on morphine-induced rats....

Full description

Bibliographic Details
Main Authors: Na Yan, Ning Chen, Honghua Zhu, Jianguo Zhang, Moira Sim, Yu Ma, Wei Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3828386?pdf=render