A V530I Mutation in c-KIT Exon 10 Is Associated to Imatinib Response in Extraabdominal Aggressive Fibromatosis

Aggressive fibromatosis (AF) or desmoid tumor is a rare condition, characterized by deep tissue invasion by a monoclonal fibroblastic neoplasm, developed from musculoaponeurotic structures. Surgery is the treatment of choice, but negative margins can hardly been achieved in large tumors, and can lea...

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Bibliographic Details
Main Authors: Jean-Emmanuel Kurtz, Irène Asmane, Anne-Claire Voegeli, Agnès Neuville, Armelle Dufresne, Valère Litique, Christine Chevreau, Jean-Pierre Bergerat
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Sarcoma
Online Access:http://dx.doi.org/10.1155/2010/458156