How do PrPSc Prions Spread between Host Species, and within Hosts?

Prion diseases are sub-acute neurodegenerative diseases that affect humans and some domestic and free-ranging animals. Infectious prion agents are considered to comprise solely of abnormally folded isoforms of the cellular prion protein known as PrPSc. Pathology during prion disease is restricted to...

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Bibliographic Details
Main Author: Neil A. Mabbott
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/6/4/60