Mitochondrial hyperactivity as a potential therapeutic target in Parkinson’s disease

Mitochondrial dysfunction is thought to contribute to neurodegeneration in Parkinson’s disease (PD), yet the cellular events that lead to mitochondrial disruption remain unclear. Post-mortem studies of PD patient brains and the use of complex I inhibitors to model the disease previously suggested a...

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Bibliographic Details
Main Authors: Danielle E. Mor, Coleen T. Murphy
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2020-01-01
Series:Translational Medicine of Aging
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2468501120300171