An approach to identify new antihypertensive agents using Thermolysin as model: In silico study based on QSARINS and docking
Thermolysin is a bacterial proteolytic enzyme, considered by many authors as a pharmacological and biological model of other mammalian enzymes, with similar structural characteristics, such as angiotensin converting enzyme and neutral endopeptidase. Inhibitors of these enzymes are considered therape...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-12-01
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Series: | Arabian Journal of Chemistry |
Online Access: | http://www.sciencedirect.com/science/article/pii/S187853521630171X |