An approach to identify new antihypertensive agents using Thermolysin as model: In silico study based on QSARINS and docking

Thermolysin is a bacterial proteolytic enzyme, considered by many authors as a pharmacological and biological model of other mammalian enzymes, with similar structural characteristics, such as angiotensin converting enzyme and neutral endopeptidase. Inhibitors of these enzymes are considered therape...

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Bibliographic Details
Main Authors: Yudith Cañizares-Carmenate, Karel Mena-Ulecia, Yunier Perera-Sardiña, Francisco Torrens, Juan A. Castillo-Garit
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Arabian Journal of Chemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S187853521630171X