hTERT Promotes CRC Proliferation and Migration by Recruiting YBX1 to Increase NRF2 Expression

hTERT Promotes CRC Proliferation and Migration by Recruiting YBX1 to Increase NRF2 Expression

High human telomerase reverse transcriptase (hTERT) expression is related to severe Colorectal Cancer (CRC) progression and negatively related to CRC patient survival. Previous studies have revealed that hTERT can reduce cancer cellular reactive oxygen species (ROS) levels and accelerate cancer prog...

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Bibliographic Details
Main Authors: Chunli Gong, Huan Yang, Sumin Wang, Jiao Liu, Zhibin Li, Yiyang Hu, Yang Chen, Yu Huang, Qiang Luo, Yuyun Wu, En Liu, Yufeng Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
hTERT
NRF2
colorectal cancer
progression
YBX1
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.658101/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.658101/full

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