Environmental and pharmacological modulations of cellular plasticity: Role in the pathophysiology and treatment of depression
Atrophy of neurons and gross structural alterations of limbic brain regions, including the prefrontal cortex (PFC) and hippocampus, have been reported in brain imaging and postmortem studies of depressed patients. Preclinical findings have suggested that prolonged negative stress can induce changes...
Main Authors: | Kristie T. Ota, Ronald S. Duman |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2013-09-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996112002082 |
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