Effect of particle size on solubility, dissolution rate, and oral bioavailability: evaluation using coenzyme Q10 as naked nanocrystals

Jiao Sun,1 Fan Wang,1,2 Yue Sui,1 Zhennan She,1 Wenjun Zhai,1 Chunling Wang,1 Yihui Deng11College of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China; 2Beijing Zhijianjinrui Applied Pharmaceutical Science Inc, Beijing, ChinaAbstract: In this paper work, four naked nanocrystals (size ran...

Full description

Bibliographic Details
Main Authors: Sun J, Wang F, Sui Y, She Z, Zhai W, Wang C, Deng Y
Format: Article
Language:English
Published: Dove Medical Press 2012-11-01
Series:International Journal of Nanomedicine
Online Access:http://www.dovepress.com/effect-of-particle-size-on-solubility-dissolution-rate-and-oral-bioava-a11505