Structural comparison of human mammalian ste20-like kinases.

Structural comparison of human mammalian ste20-like kinases.

The serine/threonine mammalian Ste-20 like kinases (MSTs) are key regulators of apoptosis, cellular proliferation as well as polarization. Deregulation of MSTs has been associated with disease progression in prostate and colorectal cancer. The four human MSTs are regulated differently by C-terminal...

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Bibliographic Details
Main Authors: Christopher J Record, Apirat Chaikuad, Peter Rellos, Sanjan Das, Ashley C W Pike, Oleg Fedorov, Brian D Marsden, Stefan Knapp, Wen Hwa Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2920948?pdf=render

Internet

http://europepmc.org/articles/PMC2920948?pdf=render

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