Lipid‐based gene delivery to macrophage mitochondria for atherosclerosis therapy

Abstract Atherosclerosis with associated cardiovascular diseases remains one of the main causes of disability and death worldwide, requiring development of new solutions for prevention and treatment. Macrophages are the key effectors of a series of events involved in atherogenesis, such as inflammat...

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Bibliographic Details
Main Authors: Felix H. Zakirov, Dongwei Zhang, Andrey V. Grechko, Wei‐Kai Wu, Anastasia V. Poznyak, Alexander N. Orekhov
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:Pharmacology Research & Perspectives
Subjects:
Online Access:https://doi.org/10.1002/prp2.584