Physiology and Pathophysiology of Proteinase-Activated Receptors (PARs): Regulation of the Expression of PARs

The level of receptors expressed on the cell surface determines the cellular responsiveness to agonists. Proteinase-activated receptors (PARs) have been reported to be either upregulated or down-regulated in response to various types of stimulation and pathological situations. In addition, the trans...

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Bibliographic Details
Main Authors: Katsuya Hirano, Tatsuya Yufu, Mayumi Hirano, Junji Nishimura, Hideo Kanaide
Format: Article
Language:English
Published: Elsevier 2005-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S134786131932290X