Peroxisome proliferator-activated receptor delta activation leads to increased transintestinal cholesterol efflux

Peroxisome proliferator-activated receptor delta (PPARδ) is involved in regulation of energy homeostasis. Activation of PPARδ markedly increases fecal neutral sterol secretion, the last step in reverse cholesterol transport. This phenomenon can neither be explained by increased hepatobiliary cholest...

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Bibliographic Details
Main Authors: Carlos L.J. Vrins, Astrid E. van der Velde, Karin van den Oever, Johannes H.M. Levels, Stephane Huet, Ronald P.J. Oude Elferink, Folkert Kuipers, Albert K. Groen
Format: Article
Language:English
Published: Elsevier 2009-10-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520307124