Gene expression drives the evolution of dominance

Dominance is difficult to measure in natural populations as it is confounded with fitness. Here, Huber et al. developed a new approach to co-estimate dominance and selection coefficients, and found that the observed relationship is best fit by a new model of dominance based on gene expression level.

Bibliographic Details
Main Authors: Christian D. Huber, Arun Durvasula, Angela M. Hancock, Kirk E. Lohmueller
Format: Article
Language:English
Published: Nature Publishing Group 2018-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-05281-7