Treatment with Cyclic AMP Activators Reduces Glioblastoma Growth and Invasion as Assessed by Two-Photon Microscopy

(1) Background: Despite progress in surgery and radio-chemotherapy of glioblastoma (GB), the prognosis remains very poor. GB cells exhibit a preference for hypoxia to maintain their tumor-forming capacity. Enhancing oxidative phosphorylation—known as the anti-Warburg effect—with cyclic AMP activator...

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Bibliographic Details
Main Authors: Krista Minéia Wartchow, Benjamin Schmid, Philipp Tripal, Andreas Stadlbauer, Michael Buchfelder, Carlos-Alberto Gonçalves, Andrea Kleindienst
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/3/556