Plasmin plays an essential role in amplification of psoriasiform skin inflammation in mice.

BACKGROUND:Although increased levels of plasminogen activators have been found in psoriatic lesions, the role of plasmin converted from plasminogen by plasminogen activators in pathogenesis of psoriasis has not been investigated. METHODOLOGY/PRINCIPAL FINDINGS:Here we examined the contribution of pl...

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Bibliographic Details
Main Authors: Qun Li, Fang Ke, Weiwei Zhang, Xiaoyan Shen, Qiannan Xu, Hong Wang, Xue-Zhong Yu, Qibin Leng, Honglin Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3032787?pdf=render