Deep brain stimulation of the pedunculopontine nucleus modulates subthalamic pathological oscillations

Low frequency deep brain stimulation (DBS) of the pedunculopontine nucleus area (PPNa) has been proposed as a novel surgical target for gait dysfunction in the late stage of Parkinson's disease (PD). Since the mid-2000s, we have shown that intrasurgical delivery of stimulation in the pontine te...

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Bibliographic Details
Main Authors: Alessandro Stefani, Laura Clara Grandi, Salvatore Galati
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118307435