Vascular control of the Drosophila haematopoietic microenvironment by Slit/Robo signalling

The posterior signalling centre (PSC) in Drosophilalarva regulates blood cell differentiation but it is unclear how this is controlled. Here, the authors show that Slit/Robo signalling from the vascular system regulates PSC morphology and function, in turn, regulating blood cell differentiation.

Bibliographic Details
Main Authors: Ismaël Morin-Poulard, Anurag Sharma, Isabelle Louradour, Nathalie Vanzo, Alain Vincent, Michèle Crozatier
Format: Article
Language:English
Published: Nature Publishing Group 2016-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11634