A Cytochrome P450 3A4 Biosensor Based on Generation 4.0 PAMAM Dendrimers for the Detection of Caffeine

Cytochromes P450 (CYP, P450) are a large family of heme-active-site proteins involved in many catalytic processes, including steroidogenesis. In humans, four primary enzymes are involved in the metabolism of almost all xenobiotics. Among these enzymes, CYP3A4 is responsible for the inactivation of t...

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Bibliographic Details
Main Authors: Michael Müller, Neha Agarwal, Jungtae Kim
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Biosensors
Subjects:
Online Access:http://www.mdpi.com/2079-6374/6/3/44