Human Primary Epithelial Cells Acquire an Epithelial-Mesenchymal-Transition Phenotype during Long-Term Infection by the Oral Opportunistic Pathogen, Porphyromonas gingivalis

Human Primary Epithelial Cells Acquire an Epithelial-Mesenchymal-Transition Phenotype during Long-Term Infection by the Oral Opportunistic Pathogen, Porphyromonas gingivalis

Porphyromonas gingivalis is a host-adapted oral pathogen associated with chronic periodontitis that successfully survives and persists in the oral epithelium. Recent studies have positively correlated periodontitis with increased risk and severity of oral squamous cell carcinoma (OSCC). Intriguingly...

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Bibliographic Details
Main Authors: Jungnam Lee, JoAnn S. Roberts, Kalina R. Atanasova, Nityananda Chowdhury, Kyudong Han, Özlem Yilmaz
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Porphyromonas gingivalis
oral opportunistic pathogen
oral epithelial cell
epithelial-mesenchymal-transition
oral cancer
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00493/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2017.00493/full

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