Synthesis of novel tetrahydroquinoline derivatives from α,α′-bis(substituted-benzylidene)cycloalkanones

In this paper, we describe a two-step synthesis of a series of substituted tetrahydroquinoline analogies. In the first step α,α′-bis(substituted-benzylidene)cycloalkanones are reacted with malononitrile to afford 2-amino-3-cyano-4H-pyrans. The second step involves the conversion of pyrans into 2-ami...

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Bibliographic Details
Main Authors: Enayatollah Sheikhhosseini, Elinaz Farrokhi, Mohammad Ali Bigdeli
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Journal of Saudi Chemical Society
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610312001573