Effect of propofol in the immature rat brain on short- and long-term neurodevelopmental outcome.

BACKGROUND: Propofol is commonly used as sedative in newborns and children. Recent experimental studies led to contradictory results, revealing neurodegenerative or neuroprotective properties of propofol on the developing brain. We investigated neurodevelopmental short- and long-term effects of neon...

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Bibliographic Details
Main Authors: Tanja Karen, Gerald W Schlager, Ivo Bendix, Marco Sifringer, Ralf Herrmann, Christos Pantazis, David Enot, Matthias Keller, Thoralf Kerner, Ursula Felderhoff-Mueser
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3667818?pdf=render