Effect of lung lavage via fiber bronchoscope combined with non- invasive positive pressure ventilation on the blood gas results and systemic state of patients with COPD complicated by severe pneumonia

Effect of lung lavage via fiber bronchoscope combined with non- invasive positive pressure ventilation on the blood gas results and systemic state of patients with COPD complicated by severe pneumonia

Objective: To discuss the effect of lung lavage via fiber bronchoscope combined with non- invasive positive pressure ventilation on the blood gas results and systemic state of patients with COPD complicated by severe pneumonia. Methods: A total of 68 patients with COPD complicated by severe pneum...

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Bibliographic Details
Main Authors: Chang-Hao Yao, Zhao-Hua Dai, Rui-Li Chai
Format: Article
Language:English
Published: Editorial Board of Journal of Hainan Medical University 2017-11-01
Series:Journal of Hainan Medical University
Subjects:
retrospectively analyzed and then divided into the group A (n=35) who received noninvasive positive pressure ventilation and the group B (n=33) who received lung lavage via fiber bronchoscope combined with non-invasive positive pressure ventilation. The differences in arterial blood gas and serum index levels were compared between the two groups before and after treatment. Results: Before treatment
there was no statistically significant difference in arterial blood gas index levels as well as serum contents of inflammatory mediators
stress hormones and myocardial enzyme spectrum indexes between the two groups. After treatment
arterial blood gas indexes PH and PaO2 levels of group B were higher than those of group A; serum inflammatory mediators HMGB1
PCT and hs-CRP contents were lower than those of group A; serum stress hormones Cor
AngⅠ and AngⅡ contents were lower than those of group A; serum myocardial enzyme spectrum indexes α-HBDH and cTn-Ⅰ contents were lower than those of group A. Conclusion: Lung lavage via fiber bronchoscope combined with non-invasive positive pressure ventilation can effectively optimize the arterial blood gas levels
COPD
Severe pneumonia
Non-invasive positive pressure ventilation
Lung lavage via fiber bronchoscope
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