Aging and leukemic evolution of hematopoietic stem cells under various stress conditions
Abstract Hematopoietic stem cells (HSCs) have self-renewal capacity and differentiation potential into all lineages of blood cells throughout the lifetime of an organism. The function of HSCs gradually changes during aging. To date, various stress factors influencing HSC aging have been identified....
Main Authors: | Shuhei Kurosawa, Atsushi Iwama |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-11-01
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Series: | Inflammation and Regeneration |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s41232-020-00138-3 |
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