Implementing the Bruker MALDI Biotyper in the Public Health Laboratory for C. botulinum Neurotoxin Detection

Implementing the Bruker MALDI Biotyper in the Public Health Laboratory for C. botulinum Neurotoxin Detection

Currently, the gold standard method for active botulinum neurotoxin (BoNT) detection is the mouse bioassay (MBA). A Centers for Disease Control and Prevention-developed mass spectrometry (MS)-based assay that detects active BoNT was successfully validated and implemented in a public health laborator...

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Bibliographic Details
Main Authors: Michael J. Perry, Dominick A. Centurioni, Stephen W. Davis, George E. Hannett, Kimberlee A. Musser, Christina T. Egan
Format: Article
Language:English
Published: MDPI AG 2017-03-01
Series:Toxins
Subjects:
Clostridium botulinum
mass spectrometry
toxin
mouse bioassay
Online Access:http://www.mdpi.com/2072-6651/9/3/94

Internet

http://www.mdpi.com/2072-6651/9/3/94

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