Online High-throughput Mutagenesis Designer Using Scoring Matrix of Sequence-specific Endonucleases
CRISPR Cas9 and other sequence-specific endonucleases are fundamental genome editors supporting gene knockout and gene therapy. A speedy and accurate computational allele designer is required for a high through-put gene mutagenesis pipeline using these new techniques.
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2015-03-01
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| Series: | Journal of Integrative Bioinformatics |
| Online Access: | https://doi.org/10.2390/biecoll-jib-2015-283 |