Attenuation of renal fibrosis after unilateral ureteral obstruction in mice lacking the N-type calcium channel.

Attenuation of renal fibrosis after unilateral ureteral obstruction in mice lacking the N-type calcium channel.

The N-type Ca2+ channel (Cav2.2) is distributed in sympathetic nerves that innervate the tubules, the vessels, and the juxtaglomerular granular cells of the kidney. However, the role of N-type Ca2+ channels in renal disease remains unknown. To address this issue, Cav2.2 knockout mice were utilized....

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Bibliographic Details
Main Authors: Keiichiro Mishima, Masao Nakasatomi, Shunsuke Takahashi, Hidekazu Ikeuchi, Toru Sakairi, Yoriaki Kaneko, Keiju Hiromura, Yoshihisa Nojima, Akito Maeshima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0223496

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https://doi.org/10.1371/journal.pone.0223496

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