LIM kinase1 modulates function of membrane type matrix metalloproteinase 1: implication in invasion of prostate cancer cells

<p>Abstract</p> <p>Background</p> <p>LIM kinase 1 (LIMK1) is an actin and microtubule cytoskeleton modulatory protein that is overexpressed in a number of cancerous tissues and cells and also promotes invasion and metastasis of prostate and breast cancer cells. Membrane...

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Bibliographic Details
Main Authors: Chakrabarti Ratna, Ottman Richard, Tapia Tenekua
Format: Article
Language:English
Published: BMC 2011-01-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/10/1/6