Novel mouse model for evaluating in vivo efficacy of xCT inhibitor

xCT, a well-known cystine transporter, is reported to be involved in the proliferation of various cells, such as cancer cells, immune cells, and fibroblasts. xCT inhibitor is expected to be a promising drug for cancer or immune diseases. However, there are little studies reporting that xCT inhibitor...

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Bibliographic Details
Main Authors: Ryosuke Yoshioka, Yusuke Fujieda, Yamato Suzuki, Osamu Kanno, Asako Nagahira, Tomohiro Honda, Masao Murakawa, Hiroshi Yukiura
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319356889