Transport rankings of non-steroidal antiinflammatory drugs across blood-brain barrier in vitro models.

The aim of this work was to conduct a comprehensive study about the transport properties of NSAIDs across the blood-brain barrier (BBB) in vitro. Transport studies with celecoxib, diclofenac, ibuprofen, meloxicam, piroxicam and tenoxicam were accomplished across Transwell models based on cell line P...

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Bibliographic Details
Main Authors: Iveta Novakova, Eva-Anne Subileau, Stefan Toegel, Daniela Gruber, Bodo Lachmann, Ernst Urban, Christophe Chesne, Christian R Noe, Winfried Neuhaus
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24466249/?tool=EBI