DCBLD2 Affects the Development of Colorectal Cancer via EMT and Angiogenesis and Modulates 5-FU Drug Resistance

DCBLD2 Affects the Development of Colorectal Cancer via EMT and Angiogenesis and Modulates 5-FU Drug Resistance

Background: DCBLD2 is highly expressed in various cancers, including colorectal cancer. DCBLD2 overexpression promotes tumor occurrence, development, and metastasis. However, DCBLD2 sensitivity to chemotherapy drugs and its mechanism on tumor development are unknown.Methods: DCBLD2 expression differ...

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Bibliographic Details
Main Authors: Pan Xie, Fu-Qiang Yuan, Ma-Sha Huang, Wei Zhang, Hong-Hao Zhou, Xi Li, Zhao-Qian Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
colorectal cancer
5-FU
EMT
drug sensitivity
DCBLD2
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.669285/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.669285/full

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