Targeting TREM-1 signaling in the presence of antibiotics is effective against Streptococcal toxic-shock-like syndrome (STSLS) caused by Streptococcus suis

Targeting TREM-1 signaling in the presence of antibiotics is effective against Streptococcal toxic-shock-like syndrome (STSLS) caused by Streptococcus suis

Streptococcus suis (S. suis), a major swine pathogen, is also a severe threat to human health. Infection with highly virulent strains of S. suis can cause human Streptococcal toxic-shock-like syndrome (STSLS), which is associated with high serum pro-inflammatory cytokine levels and a high mortality...

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Bibliographic Details
Main Authors: Chao eYang, Jianqing eZhao, Lan eLin, Shan ePan, Lei eFu, Li eHan, Meilin eJin, Rui eZhou, Anding eZhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Anti-Inflammatory Agents
treatment targets
Triggering receptor expressed on myeloid cells-1 (TREM-1)
Streptococcus suis (S. suis)
Streptococcal toxic-shock-like syndrome (STSLS)
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2015.00079/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcimb.2015.00079/full

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