Quercetin Inhibits Cell Survival and Metastatic Ability via the EMT-Mediated Pathway in Oral Squamous Cell Carcinoma

Quercetin Inhibits Cell Survival and Metastatic Ability via the EMT-Mediated Pathway in Oral Squamous Cell Carcinoma

This study aimed to investigate whether quercetin exerts anticancer effects on oral squamous cell carcinoma (OSCC) cell lines and to elucidate its mechanism of action. These anticancer effects in OSCC cells were assessed using an MTT assay, flow cytometry (to assess the cell cycle), wound-healing as...

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Bibliographic Details
Main Authors: So Ra Kim, Eun Young Lee, Da Jeong Kim, Hye Jung Kim, Hae Ryoun Park
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Molecules
Subjects:
quercetin
oral squamous cell carcinoma cells
metastasis
cell cycle arrest
epithelial-to-mesenchymal transition
matrix metalloproteinase
transforming growth factor-β1
Online Access:https://www.mdpi.com/1420-3049/25/3/757

Internet

https://www.mdpi.com/1420-3049/25/3/757

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