HIV-1 gp41 Fusion Intermediate: A Target for HIV Therapeutics
Human immunodeficiency virus (HIV)-1 infection is initiated by the binding of gp120 envelope glyco-protein to its cell receptor (CD4) and a coreceptor (CXCR4 or CCR5), followed by a series of conformational changes in the gp41 transmembrane subunit. These changes include insertion of fusion peptide...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2010-02-01
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Series: | Journal of the Formosan Medical Association |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0929664610600290 |