KAI1 suppresses HIF-1α and VEGF expression by blocking CDCP1-enhanced Src activation in prostate cancer

<p>Abstract</p> <p>Background</p> <p>KAI1 was initially identified as a metastasis-suppressor gene in prostate cancer. It is a member of the tetraspan transmembrane superfamily (TM4SF) of membrane glycoproteins. As part of a tetraspanin-enriched microdomain (TEM), KAI1...

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Bibliographic Details
Main Authors: Park Jung-Jin, Jin Yeung, Lee Yoon-Jin, Lee Jae-Seon, Lee Yun-Sil, Ko Young-Gyu, Lee Minyoung
Format: Article
Language:English
Published: BMC 2012-03-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/12/81