Altered gene expression in blood and sputum in COPD frequent exacerbators in the ECLIPSE cohort.

Patients with chronic obstructive pulmonary disease (COPD) who are defined as frequent exacerbators suffer with 2 or more exacerbations every year. The molecular mechanisms responsible for this phenotype are poorly understood. We investigated gene expression profile patterns associated with frequent...

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Bibliographic Details
Main Authors: Dave Singh, Steven M Fox, Ruth Tal-Singer, Stewart Bates, John H Riley, Bartolome Celli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4179270?pdf=render