Deciphering cancer heterogeneity: the biological space

Most lethal solid tumors including hepatocellular carcinoma (HCC) are considered incurable due to extensive heterogeneity in clinical presentation and tumor biology. Tumor heterogeneity may result from different cells of origin, patient ethnicity, etiology, underlying disease and diversity of genom...

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Bibliographic Details
Main Authors: Stephanie eRoessler, Anuradha eBudhu, Xin Wei Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2014.00012/full