Necroptosis in Macrophage Foam Cells Promotes Fat Graft Fibrosis in Mice

Background: Fibrosis is a major grafting-related complication that leads to fat tissue dysfunction. Macrophage-induced inflammation is related to the development of fat tissue fibrosis. Necroptosis is a recently discovered pathway of programmed cell necrosis that results in severe inflammation and s...

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Bibliographic Details
Main Authors: Xihang Chen, Zilong Deng, Jingwei Feng, Qiang Chang, Feng Lu, Yi Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.651360/full