The Enzyme-Modified Comet (EMNC) Assay for Complex DNA Damage Detection

The comet assay is a versatile, simple, and sensitive gel electrophoresis–based method that can be used to measure and accurately quantify DNA damage, particularly single and double DNA strand breaks, in single cells. While generally this is used to measure variation in DNA strand break levels and r...

Full description

Bibliographic Details
Main Authors: Maria Rita Fabbrizi, Jonathan R. Hughes, Jason L. Parsons
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Methods and Protocols
Subjects:
Online Access:https://www.mdpi.com/2409-9279/4/1/14